干眼病先进诊断方法综述研究（2012-2022）
1. 香港中文大学, 眼科及视觉科学学系, 香港 999077
2. 澳门城市大学, 数据科学学院, 澳门 999078
| 摘 要： | 干眼病（Dry eye disease, DED）是最常见的眼病之一。几乎每五个人中至少有一名DED患者。在疫情期间，由于人群长时间面对蓝光显示器，戴口罩不规范等原因，干眼症的发病率更是直线上升。因此，本研究就干眼症国内外的相关研究进行综述性分析，采用Citespace工具，对DED诊断主题进行了的文献计量综述分析和文本挖掘。基于Web of Science(WOS)和Scopus数据库，共计检索获得2131条未重复的文献。本文对贡献最多的国家、作者、期刊、参考文献、学科和关键词进行了探究。并对DED先进诊断方法进行了归纳总结，结果发现，2018年为DED研究的重要爆发时间点，此外，中国在该领域贡献率排名第二，DED研究设计多个交叉学科，包括眼科学、医学、卫生、神经学等。排行靠前的几位学者均是在DED诊断标准上具有突出贡献。有关键词和热门话题提取结果可得，DED与人们的生活习惯、年龄、慢病、眼部感染外伤等具有较强的关联。此外，本文将DED诊断依据主要归纳为以下12类，包括泪液破裂时间（Tear Break-Up Time, TBUT）、泪液Ⅰ试验（Schirmer Ⅰ Test，SⅠT）、角膜荧光素染色（Cornea Fluorescein Staining，CFS）、干涉和裂隙灯图像、体内共焦显微镜图像（In Vivo Confocal Microscopy，IVCM）、睑板腺图像（Meibometry Images）、泪液渗透压（Tear Osmolarity）、蛋白质组学分析（Proteomic Analysis）、光学相干断层扫描（Optical Coherence Tomography，OCT）图像、中医诊断（Traditional Chinese Medicine，TCM）、主观诊断和人口统计学因素。最后，本文对该领域的挑战和未来展望进行了讨论。 |
| 关 键 词： | 干眼症; 眼科; 诊断; 文献计量; Citespace |
| DOI： | 10.57237/j.cmf.2022.01.001 |
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收稿日期: 2022-08-24
接受日期: 2022-09-15
在线出版日期: 2022-11-01
Advanced Diagnosis Method Analysis of the Dry Eye Disease: A Bibliographic Study (2012-2022)
1. Department of Ophthalmology & Visual Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong 999077, China
2. The Faculty of Data Science, City University of Macau, Macau 999078, China
| Abstract: | Dry eye disease (DED) is one of the most common eye diseases. There is at least one DED patient in almost every five people. Especially in the era of COVID-19, the rate of DED is inevitably increasing. The reason falls on the frequency of screen use, the inappropriate way of mask-wearing, etc. Thus, based on the international and national literature databases, this study utilizes a systematic review method on DED diagnosis. 2131 unduplicated records are extracted from Web of Science (WOS) and Scopus databases. The most contributed countries, authors, journals, references, disciplines, and keywords are recognized. Findings show that DED research has burst in 2018. China is the second contributing country in this field. Interdisciplinary is involved in this topic, including ophthalmology, medicine, healthcare, and neurology. According to the publications of the most cited authors, the most contribution falls on the DED diagnosis standard. According to the hot topics, DED has a deep relation to human daily habits, ages, chronic disease, eye infection, and trauma. Furthermore, the major diagnosing methods are clustered as 12 clusters, which are Tear break-up time (TBUT), Schirmer I test (SIT), cornea fluorescein staining (CFS), Interferometry and slit-lamp images, in vivo confocal microscopy (IVCM) images, Meibometry images, Tear osmolarity, Proteomic analysis, Optical Coherence Tomography (OCT) images, traditional Chinese medicine (TCM) diagnosis, subjective diagnosis, and demographic factors. Finally, challenges and future perspectives are discussed. |
| Keywords: | Dry Eye Disease; Ophthalmology; Diagnosis; Bibliographic Study; Citespace |
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