从“邪伏-痼疾-癥瘕”浅谈慢性肾炎的病机
北京中医药大学, 东直门医院, 北京 100700
| 摘 要： | 慢性肾炎是多种原因引起，病理表现不同的肾小球免疫性疾病，其发病机制错综复杂，常见的诱发因素包括感染（如上呼吸道感染、急性胃肠炎等在体内引起炎症反应）、环境因素以及部分化疗药物等。而中医对治疗慢性肾炎有着深刻的认识，本文通过总结吕仁和教授的肾络微型癥瘕理论，梳理出慢性肾炎“邪伏-痼疾-癥瘕”的病机主线。认为本病病性当为本虚兼有标实，病位在肺脾肾三脏。肺脾肾功能失调为慢性肾炎的病机关键。该以本虚为主，标实为辅，肺卫失宣、脾土郁滞，肾失封藏是本病的发病基础，本虚以肺脾肾气虚为主，标实主要湿、瘀、痰、热、毒等病理产物蕴蓄在体内，从而出现痰浊、瘀血、湿毒、痼疾、癥瘕等表现。旨在说明吕仁和教授 “邪伏-痼疾-癥瘕”这一病机主线对治疗慢性肾炎具有指导意义，进一步加深中医临床对慢性肾炎的病机认识，丰富和发展了肾络微型癥瘕理论，为中医治疗肾病开辟新的思路和方法。 |
| 关 键 词： | 慢性肾炎; 邪伏-痼疾-癥瘕; 病机 |
| DOI： | 10.57237/j.cmrd.2022.01.004 |
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收稿日期: 2022-09-14
接受日期: 2022-10-11
在线出版日期: 2022-10-27
Talking About the Pathogenesis of Chronic Nephritis from "Evil-Chronic Disease-Symptom"
Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine, Beijing 100700, China
| Abstract: | Chronic nephritis is a glomerular immune disease with different pathological manifestations caused by a variety of reasons. Its pathogenesis is complicated. Common triggering factors include infection (such as upper respiratory tract infection, acute gastroenteritis, etc. causing inflammatory response in the body), environmental factors and Some chemotherapy drugs, etc. Traditional Chinese medicine has a profound understanding of the treatment of chronic nephritis. By summarizing Professor Lv Renhe's theory of micro-disease in the kidneys and collaterals, this paper sorts out the main line of pathogenesis of chronic nephritis "evil-sickness-disease-disease". It is believed that the nature of the disease should be regarded as both deficiency and excess, and the disease location is in the three viscera of the lungs, spleen and kidney. The dysfunction of the lung, spleen and kidney is the key to the pathogenesis of chronic nephritis, which should be mainly based on the deficiency of the root, supplemented by the actual body. Deficiency of spleen and kidney qi is the main factor, and the main pathological products such as dampness, blood stasis, phlegm, heat, and poison are accumulated in the body, resulting in the manifestations of phlegm turbidity, blood stasis, dampness toxin, chronic disease, and constipation. The purpose is to explain that the main pathogenesis of Professor Lv Renhe's "Xie Fu - chronic disease - Zheng Jia" has guiding significance for the treatment of chronic nephritis, further deepens the understanding of the pathogenesis of chronic nephritis in clinical Chinese medicine, and enriches and develops the theory of kidney and collateral micro syndrome. Open up new ideas and methods for traditional Chinese medicine treatment of kidney disease. |
| Keywords: | Chronic Nephritis; Evil—Chronic Disease—Conglomeration; Pathogenesis |
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