超声引导下针刺联合臭氧关节腔注射治疗膝骨性关节炎的临床研究
1. 上海交通大学医学院附属瑞金医院卢湾分院, 麻醉科, 上海 200020
2. 上海交通大学医学院附属瑞金医院, 麻醉科, 上海 200025
| 摘 要： | 目的：评价针刺联合臭氧关节腔注射治疗膝骨关节炎（KOA）的有效性。方法：选择本院KOA患者90例，男43例，女47例，年龄45~70岁，BMI 20.5~27.9 kg/m2。随机分为对照组（C组）和治疗组（T组），每组45例。C组：关节腔内注射臭氧；T组：针刺联合关节腔内注射臭氧。其中臭氧治疗每周1次，连续治疗4周；针刺每天1次，每周6次，连续治疗4周。记录患者治疗前、治疗开始后第1st，5th，12th，24th，48th（VAS/WOMAC）评分结果。结果：两组患者治疗后1st，5th，12th，24th，48th VAS评分与治疗前相比显著降低（p<0.001）。与对照组相比，治疗组在治疗后第1周的VAS评分显著降低（p<0.001），但从第5周开始到第48周，两组之间没有显著差异（p>0.05）。与治疗前相比，WOMAC疼痛、僵硬、身体功能和总分显著降低（p<0.001）。在第1周，治疗组患者的WOMAC疼痛、僵硬、身体功能优于对照组患者（p<0.001），但从第5周开始到第48周，两组之间没有显著差异（p>0.05）。结论：针刺联合臭氧关节腔内注射较单独关节腔内注射臭氧，疼痛控制佳，关节功能改善快。 |
| 关 键 词： | 针刺; 臭氧; 关节腔注射; 膝骨性关节炎 |
| DOI： | 10.57237/j.cmrd.2024.04.001 |
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收稿日期: 2024-09-23
接受日期: 2024-11-19
在线出版日期: 2024-12-23
Clinical Study on Ultrasound-guided Acupuncture Combined with Ozone Intra-articular Injection for the Treatment of Knee Osteoarthritis
1. Department of Anesthesiology, Ruijin Hospital Lu Wan Branch, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China
2. Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
| Abstract: | Objective To evaluate the efficacy of acupuncture combined with intra-articular ozone injection in treating of knee osteoarthritis (KOA). Methods: 90 patients with KOA, 43 males and 47 females, aged 45 ~ 70 years, with BMI of 20.5 ~ 27.9 kg/m2, were selected. They were randomly divided into control group (Group C) and treatment group (group T), with 45 cases in each group. Group C: intra-articular injection of ozone; Group T: acupuncture combined with intra-articular ozone injection. Ozone treatment was performed once a week for 4 weeks; Acupuncture was performed once a day, six times a week, for 4 weeks. Record the score results of VAS/WOMAC pre-treatment, 1st, 5th, 12th, 24th, 48th weeks post-treatment. SF-36 scores were recorded pre-treatment and 24th and 48th weeks post-treatment. Results In both groups, post-treatment VAS scores at 1st, 5th, 12th, 24th, 48th week showed a significant reduction compared to pre-treatment scores (p < 0.001). The VAS score at post-treatment 1st week was significantly lower in the treatment group compared to the control group (p < 0.001), but there was no significant difference between two groups starting from 5th to 48th week visit (p > 0.05). The WOMAC pain, stiffness, physical function, and total score indicated a significant reduction when compared to pre-treatment (p < 0.001). The WOMAC pain, stiffness, physical function was better in group T compared to the group C at the 1st week (p < 0.001), but there was no significant difference between two groups starting from 5th to 48th week visit group (p > 0.05). Conclusion Acupuncture combined with intra-articular injection of ozone is better than intra-articular injection of ozone alone, with better pain control and faster improvement of joint function. |
| Keywords: | Acupuncture; Ozone; Intra-articular Injection; Knee Osteoarthritis |
基金
| 1. | 上海市黄浦区科研项目 (HLM202106) |
| 2. | 嘉定区农业和社会事业科研项目 (JDKW-2019-W11) |
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