Clinical Medicine Frontiers is an international, peer-reviewed open access journal dedicated to advancing research the field of clinical medicine. The journal provides a rapid publication process to ensure wide dissemination of high-quality articles to scientists, professionals, and interested individuals worldwide. Our goal is to serve as an efficient, reliable, and trusted platform for scholars and readers, publishing cutting-edge research in the field.
Abstract: As we all know, the prevalence of tumors is increasing, and with the development of medical examination and treatment methods, the detection rate and cure rate of tumors in young women are gradually increasing, and many patients still want to realize their dream of parenthood after realizing the basic survival need of "saving life". However, the progression of the disease itself and treatment methods such as radiotherapy and chemotherapy will cause irreversible damage to the fertility of patients, so it is particularly important for these patients to preserve fertility as soon as possible. Fertility preservation is in the ascendant in China, and tumor patients are one of its main indications. In recent years, the technology has made significant progress, the current mature technology includes ovarian tissue cryopreservation and transfer, egg and embryo freezing, etc., due to the lack of understanding and application of specific programs by doctors, many patients miss the opportunity of fertility preservation, in order to provide patients with more scientific fertility preservation programs, this paper combines the fertility preservation related research of female tumor patients at home and abroad in recent years, and reviews the current fertility preservation programs and progress of female tumor patients.Abstract: As we all know, the prevalence of tumors is increasing, and with the development of medical examination and treatment methods, the detection rate and cure rate of tumors in young women are gradually increasing, and many patients still want to realize their dream of parenthood after realizing the basic survival need of "saving life". However, the pr...Learn More
Abstract: To investigate the differences in vitamin D levels in patients with different types of thyroid disease and to investigate the factors influencing vitamin D levels in patients with thyroid disease, this study collected clinical data from 1603 patients with thyroid disease attending the Department of Endocrinology and Metabolism of the First People's Hospital of Yunnan Province and conducted a retrospective cross-sectional study. The clinical data of 1603 patients with thyroid diseases including Graves' disease (GD), subacute thyroiditis (SAT), autoimmune thyroid disease (AITD) and hypothyroidism (HP) were collected from the Department of Endocrinology and Metabolism of yunnan First People's Hospital. Gender, age, BMI, blood lipids, thyroid hormones, thyroid autoantibodies, and serum 25-hydroxyvitamin D(25(OH)D) levels were measured. Results: (1) The level of 25(OH)D in patients with different thyroid diseases was from high to low, in the following order: GD group (29.54±7.54 ng/ml), SAT group (28.01±7.14 ng/ml), AITD group (26.97±6.58 ng/ml), HP group (25.88±6.75 ng/ml), the differences were statistically significant (P<0.05). The 25(OH)D level in GD group was significantly higher than that in other groups (P<0.05), while the 25(OH)D level in HP group was significantly lower than that in SAT group (P<0.05). (2) The changing trend of thyroid hormone levels (T3, FT3 and FT4) was consistent with that of 25(OH)D (P <0.005). (3) 25(OH)D was established as the dependent variable with multiple linear regression equation, Y = 3.80 gender + 0.058FT3-0.036 age + 28.122(female as control group). Conclusions: There were significant differences in vitamin D levels among patients with thyroid diseases, with the highest vitamin D level in GD patients and the lowest vitamin D level in HP patients. The higher the thyroid hormone level, the higher the 25(OH)D, which may be related to the strength of the immune response or the effect of thyroid hormone on vitamin D synthase. Male and high levels of FT3 were associated with increased 25(OH)D levels in thyroid patients.Abstract: To investigate the differences in vitamin D levels in patients with different types of thyroid disease and to investigate the factors influencing vitamin D levels in patients with thyroid disease, this study collected clinical data from 1603 patients with thyroid disease attending the Department of Endocrinology and Metabolism of the First People's...Learn More
