Medical Research Frontiers is an international, peer-reviewed open access journal dedicated to advancing research the field of medical research. The journal provides a rapid publication process to ensure wide dissemination of high-quality articles to scientists, professionals, and interested individuals worldwide. Our goal is to serve as an efficient, reliable, and trusted platform for scholars and readers, publishing cutting-edge research in the field.
Abstract: MBBS teaching in China faces many difficulties in both teaching and learning due to the fact that teachers and students are mostly non native English speakers. Therefore, educators in China have attempted to use different teaching methods to overcome these difficulties and improve teaching quality. Our research compares the effectiveness of PBL teaching and reverse teaching, which are very popular, in the study of internal medicine for MBBS students. Two groups (15 students) were randomly selected from the 2019 Internship of Internal Medicine for students. In the first group, PBL teaching was used for the endocrine section and PBL teaching was used for the digestion section. In the 2nd group, PBL teaching was used for the endocrine section and PBL teaching was used for the digestion section. At the end of each chapter's study, questionnaire scores and stage summary exams were given, and stage exam scores and questionnaire scores were calculated based on the learning method. The results showed that the teaching experience of using reverse teaching was better than that of PBL teaching (p<0.05), and the stage summary exam score after using reverse teaching was higher than that of PBL teaching (p<0.05). Among these students, four of them used AI to participate in their studies and found that their satisfaction with the course was significantly higher than the average (p<0.05). However, their test scores did not show a significant improvement compared to the average. According to the research results, we believe that reverse teaching has a better teaching effect in internal medicine teaching than PBL teaching, and the use of AI can significantly improve student satisfaction with the course, At the same time, we have considered the specific reasons for the above conclusions and proposed relevant improvement suggestions.Abstract: MBBS teaching in China faces many difficulties in both teaching and learning due to the fact that teachers and students are mostly non native English speakers. Therefore, educators in China have attempted to use different teaching methods to overcome these difficulties and improve teaching quality. Our research compares the effectiveness of PBL tea...Learn More
Abstract: Objective An economic evaluation of polyethylene glycol losenatide (PEX168) for the treatment of type 2 diabetes mellitus (T2DM). Methods Based on clinical trial data, Markov models were constructed to simulate and predict the long-term cost and utility of each regimen of placebo, PEX168/100 μg, and PEX168/200 μg. Results After simulating 30 years of disease progression, patients in the PEX168/100 μg and PEX168/200 μg groups had a 2.72% and 18% reduction in mortality compared to the placebo group, respectively. Treatment with PEX168/100 μg and PEX168/200 μg increased the utility value by 3.96, 8.21 QALYs with ICER of $20,551.53/QALYs and $25,218.80/QALYs, respectively, which is less than the threshold (λ) i.e., $85,698, and the increase in cost is acceptable, as compared to the placebo group. The results of the sensitivity analysis with cost ± 20%, utility value ± 10%, and discount rate 0 to 8% adjustments verified the stability of the model. The results of the probabilistic sensitivity analysis showed that the probability that PEX168/100 μg and PEX168/200 μg are economical when the willingness-to-pay value is λ is 99.99%. and that treatment with PEX168/200μg was more cost-utility than PEX168/100μg. Conclusion For patients with T2DM, treatment with PEX168 is the more cost-utility option.Abstract: Objective An economic evaluation of polyethylene glycol losenatide (PEX168) for the treatment of type 2 diabetes mellitus (T2DM). Methods Based on clinical trial data, Markov models were constructed to simulate and predict the long-term cost and utility of each regimen of placebo, PEX168/100 μg, and PEX168/200 μg. Results After simulating 30 years ...Learn More
